Asked user to check audio statistics when issue happen next time. Also, asked user when issue happen next time HOLD/UNHOLD option. But, Issue doesn't restore. During one-x logs investiagtion I found SRTP issue.
We see below in logs for bad calls, SRTP active inbetween call and thats reason users observing this issue.
I would be checking what is happening with RTP packets when we see the following in sniffer.
[06/07/2018 13:19:38:245] DBG: MEDIA: [3e2c] SrtpCryptoContext::CryptoContext::Update: SSRC change from 0x280863AD to 0x5003EB72
[06/07/2018 13:19:38:245] DBG: MEDIA: [3e2c] SrtpCryptoContext::CryptoContext::Update: SSRC:0x5003EB72 Initialize ROC: 0, sequence: 0, index: 0
[06/07/2018 13:19:43:562] ERR: AUDIO: [3e2c] WebRTCAudioAdapter::CallbackOnError(): channel: 10020, error: -1